nderstanding meningococcal carriage and disease in healthy teenagers

Not Applicable

Completed

• Conditions: Topic: Children, Primary Care; Subtopic: All Diagnoses, Other Primary Care; Disease: All Diseases, All Diseases; Infections and Infestations

• Registration Number: ISRCTN72009783
• Lead Sponsor: niversity of Oxford (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-12-10
• Study Completion: 2015-08-31
• Last Update Posted: 24 August 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 18000

Inclusion Criteria

1. Participant is willing and able to give informed consent for participation in the study
2. Male or female
3. In school years 12 or 13 (S5 and S6 in Scotland) and aged 15-19 years in full time or part time education, or aged 16-19 years in the general community

Target Gender: Male & Female; Upper Age Limit 19 no age limit or unit specified; Lower Age Limit 15 no age limit or unit specified

Exclusion Criteria

1. Not willing or able to give informed consent
2. Outside the specified age range

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rates of oropharyngeal carriage of Neisseria meningitidis measured at baseline as determined by culture of Neisseria meningitidis from a throat swab

Secondary Outcome Measures

Name	Time	Method
<br> 1. To determine rates of meningococcal carriage according to the serogroup and genogroup of cultured organisms from the throat swab<br> 2. To identify risk factors associated with meningococcal carriage as determined by answers to a one-page questionnaire<br> 3. To evaluate the relationship between salivary antibodies, smoking and meningococcal carriage as determined by measurements from saliva samples from Glasgow students<br>