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临床试验/NCT04830995
NCT04830995已完成不适用

Impact of High-Intensity Interval Training on Insulin Resistance During Pregnancy: A Randomized Control Trial.

Cairo University2 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2020年3月24日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
2
主要终点
Fasting blood glucose level

研究概览

简要总结

Insulin Resistance is one of the common complications that occur during pregnancy. Early intervention is essential to prevent the development of the diseaseThere is evidence that physical inactivity increases the risk of a lot of adverse health problems, including coronary heart disease, type 2 diabetes, breast and colon cancers. It also shortens life expectancy. Pregnancy is a period in the life of women that is often associated with decreased daily physical activity and decreased participation in sports and exercise . In the first few weeks of pregnancy, maternal carbohydrate metabolism is affected by a rise in maternal levels of estrogen and progesterone that stimulates pancreatic β-cell hyperplasia and insulin secretion. As pregnancy progress, pancreatic islet cell hypertrophy continues and there is an increased insulin response to glucose or meal stimulation.

详细描述

This study was carried out upon twenty multigravida pregnant female between 5-6 months gestation with IR calculated by HOMA test (fasting blood glucose× fasting insulin) ÷ 22.5. Fasting blood glucose was assessed by the method approved by (7, 13) .The test materials for this method were supplied as kits by "Diamond Diagnostics," while Insulin concentrations were stated in formerly frozen and defrosted serum samples by enzyme immunoassay using the human Insulin ELISA kits.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

盲法说明

Randomization was done by sealed envelope

入排标准

年龄范围
25 Years 至 35 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • forty multigravida females.
  • their age ranged between 25 to 35 years old.
  • Body mass index (BMI) <30kg/ m².

排除标准

  • females with pelvic pathology as endometriosis.
  • females have irregular menstrual cycles.

结局指标

主要结局

Fasting blood glucose level

时间窗: three months

Fasting blood glucose level were measured by expert specialist before and after intervention period from 24th to 37th weeks of pregnancy.

次要结局

  • Fasting Insulin Level(three months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ghada Ebrahim El Refaye

assistant professor Department of Physical Therapy for Women's Health, Faculty of Physical therapy, Cairo University, Egypt

Cairo University

研究点 (2)

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