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Clinical Trials/NL-OMON43743
NL-OMON43743
Recruiting
Not Applicable

Female subfertility: a first sign of metabolic and cardiovascular anomalies? - Female subfertility: a metabolic and vascular profile

Medisch Universitair Ziekenhuis Maastricht0 sites516 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
metabool syndroom, veneuze reservacapaciteit, endotheelfunctie
Sponsor
Medisch Universitair Ziekenhuis Maastricht
Enrollment
516
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Sponsor
Medisch Universitair Ziekenhuis Maastricht

Eligibility Criteria

Inclusion Criteria

  • Study 1\*The metabolic syndrome and female subfertility\* :
  • Study group:
  • \- primary subfertility, defined as having no previous pregnancy, or secondary subfertility, defined as a fertility problem after an ongoing pregnancy
  • \- age 18 \* 41 years
  • Control group:
  • \- women with an uneventful pregnancy in history
  • \- at least 6 months post partum
  • \- age 18 \* 41 years;Study 2 \*The cardiovascular profile in female subfertility\*:
  • Study groups:
  • \- primary subfertility, defined as having no previous pregnancy, or secondary subfertility, defined as a fertility problem after an ongoing pregnancy

Exclusion Criteria

  • Study 1 \*The metabolic syndrome and female subfertility\*
  • There are no exclusion criteria for the study of the metabolic syndrome in the subfertile women.
  • For the control group exclusion criteria are:
  • \- current pregnancy
  • \- hormonal medication
  • \- breastfeeding;Study 2 \*The cardiovascular profile in female subfertility\*
  • For the studies of the measurement of the uterine artery PI, plasma volume, intima media thickness and endothelial function exclusion criteria in all women are:
  • \- hypertension, defined as a blood pressure exceeding 140 mm Hg systolic or 90 mm Hg diastolic, or the use of antihypertensive medication
  • \- diabetes mellitus, defined as a fasting glucose level above 6,1 mmol/L or the use of antidiabetic medication
  • Additional exclusion criteria for the control group:

Outcomes

Primary Outcomes

Not specified

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