IRCT20240122060763N1RecruitingPhase 3
A comparative study of the effect of two drugs, atorvastatin and glucophage, on plasma insulin resistance and follicular fluid changes (the amount of antioxidants and oocyte growth factors) in women with polycystic ovary syndrome.
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Recruiting
- Enrollment
- 50
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to 40 years (—)
- Sex
- Female
Inclusion Criteria
- •According to the Rotterdam criteria (the presence of two criteria for the diagnosis of polycystic ovaries 1- oligomenorrhea or amenorrhea 2- clinical or laboratory findings of hyperandrogenism 3- the presence of polycystic ovaries in ultrasound examination) the diagnosis of PCOS has been confirmed in them
- •Age 18-40 years
- •Absence of thyroid disorder, Cushing's syndrome, hyperprolactinoma
- •Absence of kidney disease, liver disease, diabetes, lipid profile disorder
- •No history of cardiovascular disease and blood pressure
- •Not using ovarian stimulation drugs or hormonal drugs in the last 3 months
- •Not using insulin-sensitive drugs or lipid profiles in the last 3 months
- •not smoking
- •non-alcoholic
- •No use of addictive substances
- •Not having breast cancer
- •Absence of medicinal contraindications
- •Absence of malabsorption
- •Having a minimally abnormal amount of insulin resistance
Exclusion Criteria
- •Body mass more than 30 kg/m2
- •Body mass less than 19 kg/m2
Investigators
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