The effect of Hyaluronic Acid in repair of ear drum
Not Applicable
- Conditions
- Tympanoplasty.Perforation of tympanic membraneH72.0,H72.
- Registration Number
- IRCT2014020915496N9
- Lead Sponsor
- Vice Chancellor of Research, Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
patients more than 18 years old; tympanic perforation =50 %.
Exclusion criteria: Patients suffered from underlying diseases such as: asthma, diabetes, coagulation disorders, cardiovascular disease, basic metabolic disorder, immune system deficiency and chronic liver or renal disease; Smokers; Revision tympanoplasty; Patients with contra-lateral ear disease; Presence of cholesteatoma; Presence of tympanosclelerotic plaque in middle ear; Presence of granulation tissue in middle ear.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tympanic membrane graft success rate. Timepoint: within 6 months after surgery. Method of measurement: Observation by physician.;Hearing threshold. Timepoint: before operation, 6 months after operation. Method of measurement: pure tone audiometry.
- Secondary Outcome Measures
Name Time Method