NL-OMON29443
Recruiting
Not Applicable
A prospective randomised controlled trial in the treatment of anal fissures; Botulin-A Toxin versus Topical Diltiazem: BOTTOM-trial.
B.A. Twigt, E.A te Velde, L. Stoker, E. Kuck, A. Pronk0 sites164 target enrollmentTBD
ConditionsAnal fissure (NLD: anale fissuur).
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Anal fissure (NLD: anale fissuur).
- Sponsor
- B.A. Twigt, E.A te Velde, L. Stoker, E. Kuck, A. Pronk
- Enrollment
- 164
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
/A
Investigators
Eligibility Criteria
Inclusion Criteria
- •Chronic anal fissure, without previous therapy.
Exclusion Criteria
- •1\. Allergy to botuline A toxine and Diltiazem;
- •2\. Cardiovascular disease:
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
Results of cast treatment and percutaneous achilles tendon lengthening for children with an achilles tendon contracture.idiopatic toe walkers: children who walked on their toes after de age of two and children who has a symptomatic equinus contracture (ankle dorsiflexion between -10 and 3 degree).NL-OMON21028wetenschapsbureau Linneus Instituut Spaarne ziekenhuis78
Recruiting
Not Applicable
An independent prospective randomised controlled trial comparing the efficacy and cost effectiveness of infliximab and etanercept in 'high need' patients with moderate to severe chronic plaque type psoriasis.Psoriasis, Etanercept, Infliximab, Cost-effectiveness (kosteneffectiviteit)NL-OMON23276Academic Medical Center (AMC), Department of dermatology120
Not yet recruiting
Phase 1
A clinical trial to evaluate the effectiveness of autogenous tooth graft for socket preservatioCTRI/2024/03/064825Tanya Singh
Completed
Not Applicable
Effectiveness of auditory training in children with (central) auditory processing disorders.auditieve verwerkingsproblemen - auditory processing disorderseffectstudie - effictivenessgerandomiseerde interventie studie - randomized controlled trialkind - childNL-OMON21982MC Utrecht108
Recruiting
Not Applicable
A controlled study examining CBT for bereaved children.The death of a loved one in childhood and adolescence is a risk factor for distress and dysfunction. This event has been associated with increased emotional problems including elevated depression, anxiety, and posttraumatic stress, as well as somatic complaints and behavioural problems (Dowdney, 2008Kaplow, Layne, & Pynoos, 2012). An estimated 5% to 10% of children, experience clinically significant psychiatric problems following loss, including major depression, posttraumatic stress-disorder (PTSD), and Prolonged Grief Disorder (PGD) (Melhem, Moritz, Walker, Shear, & Brent, 2007Melhem, Porta, Shamseddeen, Walker, & Brent, 2011).PGD encompasses several symptoms including separation distress, preoccupation with thoughts about the lost person, a sense of purposelessness about the future, numbness, bitterness, difficulties accepting the loss and difficulty moving on with life without the lost person (Prigerson et al., 2009Shear et al., 2011). Although PGD has mostly been studied among adults, a growing body of empirical studies has shown that children and adolescents can develop PGD symptoms, that can be reliably assessed, are distinct from normal grief, depression and anxiety, including PTSD, and are predictive of significant concomitant internalizing and externalizing problems (Brown & Goodman, 2005Dillen, Fontaine, & Verhofstadt-Denève, 2008Spuij, Prinzie et al., 2012Spuij, Reitz et al., 2012). Evidence that, in a small percentage of people, acute grief reactions turn into chronic debilitating distress, blocking reestablishment of normal routines, will likely lead to the inclusion of two bereavement-related disorders in the DSM-5, namely Adjustment Disorder Related to Bereavement, located in its main text, and Persistent Complex Bereavement-Related Disorder, located in its appendix (APA, 2000APA, 2012for discussions see Boelen & Prigerson, 2012Kaplow et al., 2012Wakefield, 2012).NL-OMON25798niversiteit UtrechtFaculteit Sociale WetenschappenDepartement Kinder- en JeugdstudiesPostbus 801403508 TC UTRECHTNederland160