tility of real-time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in diagnosis of sarcoidosis; comparison with transbronchial lung biopsy (TBLB)
Phase 3
- Conditions
- Sarcoidosis
- Registration Number
- JPRN-UMIN000000507
- Lead Sponsor
- agoya Medical Center
- Brief Summary
Of the 62 patients enrolled, 54 were given a final diagnosis of sarcoidosis. The diagnostic yield of EBUS-TBNA and TBLB for sarcoidois by showing noncaseating epithelioid cell granuloma was 94% (stage I, 97%; stage II, 88%) and 37% (stage I, 31%; stage II, 50%), respectively. The difference was statistically significant (p<0.001). One pneumothorax and 3 moderate bleeding cases (7%) resulted from TBLB, and 1 severe cough case (2%) from EBUS-TBNA.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
1. Serious concomitant medical illness 2. Obvious bleeding tendency 3. Pregnancy 4. Other clinical difficulties in this study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sensitivity of pathological diagnosis of sarcoidosis
- Secondary Outcome Measures
Name Time Method Frequency of adverse effects