NCT00270426终止不适用
Benazepril for Advanced Chronic Renal Insufficiency
Southern Medical University, China0 个研究点开始时间: 2005年12月26日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
研究概览
简要总结
The purpose of this study is to further determine whether benazepril, could safely slow the progression of renal dysfunction in non-diabetic patients with advanced renal insufficiency.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •serum creatinine concentration 1.5-5.0 mg/dL (133-442 µmol/L)
- •creatinine clearance 20 to70 mL/min/1.73 m2, with variations of less than 30 percent in the three months before the screening evaluation
- •non-diabetic renal disease
- •persistent proteinuria (defined as urinary protein excretion greater than 0.3 g/day for three or more months without evidence of urinary-tract infection or overt heart failure [New York Heart Association class III-IV]).
排除标准
- •immediate need for dialysis; treatment with corticosteroids, non-steroidal anti-inflammatory drugs or immunosuppressive drugs; renovascular disease; myocardial infarction or cerebrovascular accident in the year preceding the trial; connective-tissue disease; obstructive uropathy.
研究者
相似试验
终止
不适用
Long-Term Renoprotection of Optimal Antiproteinuric Doses of Benazepril and Losartan in Chronic Renal InsufficiencyRenal Insufficiency,ChronicDisease ProgressionProteinuriaDose-Response Relationship,DrugACE InhibitorAngiotensin II Type 1 Receptor BlockersNCT00338091Southern Medical University, China
Unknown
1 期
Renal Effects of an Angiotensin Converting Enzyme Inhibitor in Adults With Chronic Kidney Disease of Uncertain AetiologyRenal Insufficiency, ChronicNCT01624064Ministry of Health, Sri Lanka200
终止
不适用
Safety of Dual Blockage of Rennin-angiotensin System in Patients With Advanced Renal InsufficiencyRenal Insufficiency, ChronicNCT00630708Nanfang Hospital, Southern Medical University309
已完成
2 期
Study for Secondary Hyperparathyroidism in Chronic Renal Insufficiency PatientsSecondary HyperparathyroidismChronic Renal InsufficiencyNCT00042432Amgen54
Unknown
1 期
Influence of Catheter-based Renal Denervation in Diseases With Increased Sympathetic ActivityHeart Rhythm DisordersHypertensionHeart FailureDiabetesChronic Kidney DiseaseNCT01888315University Hospital, Saarland1,000