Study on clinical efficacy of combination therapy with Bie Jia Ruan Gan Jian Pi Fang and Entecavir in the treatment of compensated patients with liver cirrhosis related to hepatitis B
- Conditions
- compensation period for liver cirrhosis related to hepatitis B
- Registration Number
- ITMCTR2100005358
- Lead Sponsor
- TCM-Integrated Hospital of Southern Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1)meet the western medical diagnostic criteria for the compensation period for liver cirrhosis related to hepatitis B; (2)meet the diagnostic criteria for Chinese medicine for Gan Dan Shi Re Jia Yu;(3)meet the antiviral standards for hepatitis B;(4)not use any antiviral drugs other than Entecavir within 3 months of diagnosis;(5)age 18-65 years old at the time of diagnosis, gender unlimited;(6)Informed consent and treatment and treatment-related laboratory examination, and can answer questions truthfully.
(1) Testing for sero HIV; (2) combining other viral liver diseases, non-alcoholic fatty hepatitis, explicit drug-damaging liver disease, self-free liver and other chronic liver diseases; (3) the combination of other chronic severe hepatitis, liver cirrhosis, liver cancer and other serious or terminal liver disease; (4) other diseases seriously affect their quality of life. If there are severe organ dysfunction and severe diabetes, liver and kidney syndrome, liver and lung syndrome or other severe trauma caused by liver disease;
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method fibroscan;color Doppler ultrasound of liver, bile, pancreas and spleen;
- Secondary Outcome Measures
Name Time Method liver function;Symptom & Signs;serum indices of hepatic fibrosis;HBV marker;APRI score;FIB-4 score;HBV-DNA;