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Role of Wound Irrigation After Appendectomy

Not Applicable
Completed
Conditions
Appendicitis
Interventions
Procedure: Irrigation
Registration Number
NCT03773224
Lead Sponsor
Mansoura University
Brief Summary

Surgical site infection is a common problem after open appendectomy. Irrigation of the surgical wound by topical antibiotics has been devised as a measure to reduce the incidence of wound infection. The present trial aims to assess the efficacy of layer-by-layer wound irrigation with gentamicin-saline solution in prevention of superficial surgical site infection after open appendectomy for acute uncomplicated appendicitis.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
179
Inclusion Criteria
  • Adult patients of both genders aging between 18 and 65 years who present with acute appendicitis.
  • Patients with perforated appendicitis will be also included.
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Exclusion Criteria
  • Patients with appendicular mass, appendicular abscess, generalized peritonitis.
  • Patients with other causes of acute abdomen as revealed intraoperatively.
  • Patients taking long course of steroid therapy or immunosuppressive treatment,
  • Patients unwilling to participate in the trial.
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
IrrigationIrrigationLayer by layer irrigation of the surgical wound with gentamicin-saline solution
Primary Outcome Measures
NameTimeMethod
Surgical site infection2 months after surgery

The incidence of superficial site infection as detected by clinical examination on follow-up

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Mansoura university hospital

🇪🇬

Mansourah, Dakahlia, Egypt

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