CABG Off or On Pump Revascularization Study (CORONARY) - CORONARY

Population Health Research Institute0 个研究点目标入组 4,700 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Patients who have been diagnosed with coronary artery disease (single, double or triple disease) will be eligible if they:
•1.require isolated CABG with median sternotomy
•2.are able to give their informed written consent
•3.are above 21 years of age and
•4.have one or more of the following risk factors:
•â?¦above or equal to 70 years
•â?¦peripheral vascular disease (previous peripheral bypass or amputation or ABI less than 0.80)
•â?¦Cerebrovascular disease (history of stroke, TIA)
•â?¦Renal insufficiency (creatinine above upper limit of normal)
•â?¦above 60 years of age and one of the following:
•â? diabetes (oral hypoglycemic agent and/or insulin)
•â? urgent revascularization (waiting in hospital)
•â? LV ejection fraction below 35 percent
•â? current or recent smoker.
•â?¦55-59 years of age and two of the following:
•â? diabetes (oral hypoglycemic agent and/or insulin)
•â? urgent revascularization (waiting in hospital)
•â? LV ejection fraction below 35 percent
•â? current or recent smoker.

•Patients will be excluded if they have one of the following:
•1.concomitant cardiac procedure associated with CABG,
•2.contra-indications to off-pump CABG or on-pump CABG (calcified aorta, intramuscular LAD, calcified coronaries, small target vessels)
•3.concomitant life-threatening disease likely to limit life expectancy to less than 2 years,
•4.prior enrollment in this trial
•5.emergency CABG surgery (immediate revascularization for hemodynamic instability) OR
•6.redo CABG.

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