4DCT Wrist Biomarkers During Resisted and Unresisted Tasks in Healthy Controls
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 31
- 试验地点
- 1
- 主要终点
- Radiolunate (RL) Gapping
研究概览
简要总结
The purpose of this study is to use CT motion pictures (4DCT) to visualize and record how much space there is between certain wrist joint bones, both without any resistance and with light resistance to the movement, during a single scanning visit.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Inclusion Criterion:
- •Age ≥ 18 and ≤ 60 years.
- •Control subjects without any history of wrist injury or disease.
排除标准
- •(applied to both wrists for control subjects):
- •Previously-diagnosed rheumatological conditions or connective tissue diseases;
- •Inability to be appropriately positioned in the scanner for the imaging;
- •Congenital malformations of the wrist or forearm;
- •Diagnosed wrist osteoarthritis
- •Age under 18 or over 60.
研究组 & 干预措施
Healthy Controls
干预措施: 4DCT (Device)
结局指标
主要结局
Radiolunate (RL) Gapping
时间窗: Baseline
Normalized volar/dorsal location of the gapping at the radiolunate joint, measured in millimeters, at each of the 17 time steps during each movement.
Scapholunate (SL) Gapping
时间窗: Baseline
Normalized volar/dorsal location of the gapping at the scapholunate joint, measured in millimeters, at each of the 17 time steps during each movement.
Radioscaphoid (RS) Gapping
时间窗: Baseline
Normalized volar/dorsal location of the gapping at the radioscaphoid joint, measured in millimeters, at each of the 17 time steps during each movement.
次要结局
- Trapezoitrapezoid (TmTd) Gapping(Baseline)
- Scaphotrapezoid (STd) Gapping(Baseline)
- Scaphotrapezium (STm) Gapping(Baseline)
研究者
Kristin Zhao, PhD
Principal Investigator
Mayo Clinic