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Dual Arterial Phase Liver CT in Patients With Suspected Portal Hypertension

Not Applicable
Conditions
Cirrhosis, Liver
HCC
Interventions
Diagnostic Test: Liver CT
Registration Number
NCT04195971
Lead Sponsor
Seoul National University Hospital
Brief Summary

Patients with liver cirrhosis is at risk of developing HCC. To diagnose or detect HCC at CT/MRI, optimal late arterial phase (LAP) acquisition is critical to capture the tumor. For LAP acquisition, bolus-tracking is often used at CT. In patients with portal hypertension, however, bolus-tracking occasionally capture early arterial phase which may be related with slow portomesenteric flow. In this study, we obtain dual arterial phase in patients with suspected portal hypertension and determine whether this protocol (dual arterial phase) would provide higher incidence of LAP acquisition than single arterial phase acquisition.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
69
Inclusion Criteria
  • Older than 20 years
  • Liver cirrhosis diagnosed with characteristic imaging feature or histology
  • Presence of portal hypertension sign (splenomegaly and varices)
  • Scheduled for liver CT
  • And signed informed consent
Exclusion Criteria
  • Relative or absolute contra-indication of contrast-enhanced CT

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Liver CT with dual arterial phaseLiver CT-
Primary Outcome Measures
NameTimeMethod
Incidence of optimal late arterial phase acquisition1 months after study completion

incidences of optimal late arterial phase acquisition in 1st and 2nd acquisition of arterial phase in this protocol (dual arterial phase) CT.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Seoul National University Hospital

🇰🇷

Seoul, Korea, Republic of

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