The Effect of Dexmedetomidine on Decreasing Emergence Agitation and Delirium in Pediatric Patients Undergoing Strabismus Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Dexmedetomidine
- Conditions
- Strabismus
- Sponsor
- Yonsei University
- Enrollment
- 88
- Locations
- 1
- Primary Endpoint
- objective pain score
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Postoperative agitation in children is a well-documented clinical phenomenon with incidence ranging from 10% to 67%. Recently, dexmedetomidine has been investigated extensively in the pediatric population and there is now increasing evidence to support the use of this drug as sedative and anesthetic adjunct in children. The purpose of this study is to determine whether prophylactic use of intraoperative dexmedetomidine to prevent of emergence delirium.
Investigators
Eligibility Criteria
Inclusion Criteria
- •the patient undergoing the strabismus surgery in severance hospital
Exclusion Criteria
- •delayed development
- •mental retardation
- •cerebral palsy
- •preoperative EKG abnormality e.g. cardiovascular conduction disorder
Arms & Interventions
dexmedetomidine
Intervention: Dexmedetomidine
placebo
Intervention: placebo group
Outcomes
Primary Outcomes
objective pain score
Time Frame: immediate postoperative period up to 1hour after surgery
1. Objective pain score(OPS) Blood pressure 0\~2 points crying 0\~2points movement 0\~2points agitation 0\~2points posture 0\~2points complain of pain(where appropiraate by age) 0\~2points total 0\~10 points
pediatric anesthesia emergence delirium (PAED) scale
Time Frame: immediate postoperative period up to 1hour after surgery
2. pediatric anesthesia emergence delirium (PAED) scale The Child makes eye contact with the caregiver 0\~4 The child's actions are purposeful. 0\~4 The child is aware of his'her surroundings. 0\~4 The child is restless. 0\~4 The child is insonsolable. 0\~4 total 0\~20 points
5-point agitation scale
Time Frame: immediate postoperative period up to 1hour after surgery
3. Scoring system for emergence agitation (behavior score) 1. Sleeping 2. Awake and calm 3. Irritable and crying 4. Inconsolable crying 5. Severe restlessness and disorientation