Effect of Oral Cryotherapy and Normal Saline Mouth Rinse on Chemotherapy –Induced Oral Mucositis in Patients with Blood Stem-Cell Transplantatio
- Conditions
- oral mucositis.oral mucositis-ulcerative
- Registration Number
- IRCT201307165665N4
- Lead Sponsor
- ursing and Midwifery Faculty- Vice chancellor for research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Consciousness; Age between 18 to 70 years; To have Hodgkin's, non Hodgkin's lymphoma or Multiple Myeloma with the same grades; To have healthy oral mucous; Isolation of participants from the beginning of the project; To have Similar Chemotherapy properties; To have the same Autologous transplantation protocols
Exclusion criteria: Participants’ dissatisfaction; Loss of consciousness; Suffering from other diseases during treatment; use of narcotic analgesics continuously before the study; Combined therapies such as radiation therapy at the time of study; Fever, neutropenia and mucositis before starting treatment; To have respiratory diseases such as asthma and oral infections; Systemic diseases effective on oral tissues, especially periodontal disease; To have chemotherapy two weeks before transplantation; Change in treatment protocol during the study
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oral Mucositis. Timepoint: before chemotherapy and 3rd, 7th, 14th and21th days folowing end of chemotherapy. Method of measurement: WHO Mucositis Scale.
- Secondary Outcome Measures
Name Time Method ausea and Vomiting. Timepoint: During 4 days, every day following end of chemotherapy. Method of measurement: checklist.