Premature Umbilical Cord Blood (PUCB).
Completed
- Registration Number
- NL-OMON27961
- Lead Sponsor
- Project 945-04-609 of ZonM/wProject OOPEP/1044 of Sanquin Blood supply
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 600
Inclusion Criteria
1. Pregnant women;
2. Premature (gestational age of < 36 weeks) who require a red blood cell transfusion.
Exclusion Criteria
1. Hemolytic disease of the newborn;
2. Maternal infections such as HIV/HCV/HBV/CMV/ Toxoplasma/ Treponema pallidum or maternal septicaemia;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients who received allogeneic transfusions and the total volume of administered allogeneic red cells.<br>Days of support of vital functions in the NICU.<br>
- Secondary Outcome Measures
Name Time Method 1. Days of assisted ventilation support;<br /><br>2. Cumulative complication incidence<br /> (infections, cerebral events); <br /><br>3. Length of hospital stay;<br /><br>4. Mortality;<br /><br>5. Feasibility of erythrocyte collection from cord blood;<br /><br>6. Costs of transfusions;<br /><br>7. Costs of care;<br /> <br>8. 2 year and 5 years neurodevelopmental follow-up.