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Clinical Trials/NCT00440856
NCT00440856
Completed
Not Applicable

Reduction in Leg and Back Pain Following Lumbar Microdiscetomy in Those Shown the Removed Disc Fragments After the Operation: a Double Blind Randomized Control Trial.

St George's, University of London1 site in 1 country100 target enrollmentFebruary 2007
ConditionsRadiculopathy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Radiculopathy
Sponsor
St George's, University of London
Enrollment
100
Locations
1
Primary Endpoint
Subjective experience of radiculopathic pain by the patient following surgery
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The trial aims to assess the hypothesis that presentation of the disc material to the patient following a lumbar microdiscectomy would positively influence the improvement in their leg and back symptoms.

Detailed Description

Objective. The trial aims to assess the hypothesis that presentation of removed material to the patient following a lumbar microdiscectomy would positively influence the improvement in their radiculopathic and degenerative symptoms. Design. Data will be collected prospectively. Patient allocation to treatment groups will be by simple randomization using a computer generated sequence of random numbers. Trial participants will be blinded as to the trial hypothesis and investigators blinded to patient allocation. Setting. Patients will all be treated in a single secondary care unit. Participants. All adult patients undergoing a planned lumbar microdiscectomy for radiculopathy due to a prolapsed intervertebral disc over a six month period will be considered for entry into the trial. Exclusion criteria: inability to give verbal consent, age less than 18, previous spinal surgery, emergency discectomies, patients having spinal fusions and those with no radiculopathic symptoms. Intervention. Patients allocated to the experimental arm will be given the removed disc fragments to keep once they have recovered from anaesthesia. Those in the control arm will not be shown disc fragments (best available treatment). Main outcome measure. The degree of improvement in radiculopathic and degenerative symptoms reported by the patient at 2-3 months after surgery.

Registry
clinicaltrials.gov
Start Date
February 2007
End Date
May 2008
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • All adult patients undergoing a planned lumbar microdiscectomy for radiculopathy due to a prolapsed intervertebral disc

Exclusion Criteria

  • inability to give verbal consent, age less than 18, previous spinal surgery, emergency discectomies, patients having spinal fusions and those with no radiculopathic symptoms.

Outcomes

Primary Outcomes

Subjective experience of radiculopathic pain by the patient following surgery

Time Frame: 2-4 months

Secondary Outcomes

  • Subjective experience of paraesthesia by the patient following surgery(2-4 months)
  • Subjective experience of lower limb motor weakness by the patient following surgery(2-4 months)
  • Maximum walking distance(2-4 months)
  • Subjective experience of numbness by the patient following surgery(2-4 months)
  • Subjective experience of low back pain by the patient following surgery(2-4 months)
  • Altered pattern of use of analgesia(2-4 months)

Study Sites (1)

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