Intrathecal Additives for Spinal Anaesthesia in Elective Caesarean Sections

Not Applicable

• Conditions: Pain, Postoperative
• Interventions: Drug: intrathecal Magnesium; Drug: intrathecal dexamthasone; Drug: intrathecal dexmedetomidine

• Registration Number: NCT04747171
• Lead Sponsor: Benha University

Brief Summary

we designed this randomized, single -blind, prospective clinical study to test postoperative analgesia of three intrathecal additives in elective caesarean sections which are magnesium, dexamethasone and dexmedetomidine.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-02
• Study First Submitted: 2021-02-05
• Study First Submitted QC: 2021-02-09
• Last Update Submitted: 2021-02-09
• Study First Posted: 2021-02-10
• Last Update Posted: 2021-02-10
• Study Start: 2021-04
• Primary Completion: 2021-06
• Study Completion: 2021-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 105

Inclusion Criteria

• American Society of Anesthesiologists classII-III adult female patient (age :18 -40 years old )
• Elective cesarean section under spinal anaesthesia
• Gestational age > 37 weeks
• BMI less than 30 kg/m2

Exclusion Criteria

• Patient refusal
• unable to give consent
• age < 18 or > 40
• BMI more than 30 kg/m2
• known allergy to the study medication
• coagulopathies or on anticoagulant medications
• diabetic neuropathy
• patients with psychiatric disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
magnesium intrathecal	intrathecal Magnesium	-
dexamethasone intrathecal	intrathecal dexamthasone	-
dexmedetomidine intrathecal	intrathecal dexmedetomidine	-

Primary Outcome Measures

Name	Time	Method
analgesic effect	Up to 24 hours after surgery	duration of sensory block