B Vitamin Deficiency and Pregnancy Complications

Withdrawn

• Conditions: Gestational Hypertension; Preeclampsia
• Interventions: Other: No intervention

• Registration Number: NCT05720650
• Lead Sponsor: Westlake University

Brief Summary

This case-control study aims to investigate the association between B vitamins and gestational hypertension or preeclampsia.

Detailed Description

In clinical practice, women diagnosed with gestational hypertension or preeclampsia will be asked to participate this study to fill a questionnaire reporting their basic information. Meanwhile, women with matched age and gestation week and without any kinds of hypertensive disorders will also be invited for this study. Participants' blood samples will be analyzed for B vitamin levels at the end of the study.

Study Timeline

• Status Verified: 2022-11
• Study First Submitted: 2022-11-14
• Study First Submitted QC: 2023-02-08
• Study First Posted: 2023-02-09
• Last Update Submitted: 2023-04-09
• Last Update Posted: 2023-04-11
• Study Start: 2023-06-01
• Primary Completion: 2024-06-01
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

• pregnant women aged 18-40 years old

Exclusion Criteria

• women with Hepatitis B, syphilis, HIV/AIDS and other infectious diseases.
• women with severe physical or mental diseases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Case subjects diagnosed with gestational hypertension or preeclampsia	No intervention	This is a restrospective observational study and there is no intervention.
Control subjects diagnosed without any hypertensive disorders	No intervention	This is a restrospective observational study and there is no intervention.

Primary Outcome Measures

Name	Time	Method
preeclampsia	seven days after delivery	Gestational hypertension is diagnosed when blood pressure readings are higher than 140/90 mm Hg in a woman who had normal blood pressure prior to 20 weeks and has positive proteinuria (excess protein in the urine).
gestational hypertension	seven days after delivery	Gestational hypertension is diagnosed when blood pressure readings are higher than 140/90 mm Hg in a woman who had normal blood pressure prior to 20 weeks and has no proteinuria (excess protein in the urine).

Trial Locations

Locations (1)

Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine; 🇨🇳 Hangzhou, Zhejiang, China