Influence of 10 Hz rTMS and noradrenergic modulation on motor learning in healthy humans

Not Applicable

• Conditions: Healthy subjects

• Registration Number: DRKS00004653
• Lead Sponsor: Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2012-10-01
• Study Start: 2013-01-16
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

healthy subjects,
right handed,
age between 18 - 45 years

Exclusion Criteria

left-handed,
neurological diseases,
psychiatric diseases,
other medical diseases,
brain injury,
stroke,
febrile seizures in the childhood,
psychotropic medication,
fine motor skills,
implanted devices like cardiac pacemaker,
any metal in the head,
pregnancy,
lactation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of motor potentials evoked by transcranial magnetic stimulation, potentials were recorded with surface EMG-electrodes from the first dorsal interosseus muscle of the left hand (peak-to-peak-amplitudes in mV): <br>resting motor threshold, short-intracortical-inhibition, intracortical facilitation, stimulus response curve<br><br>Measured by the raw data of the fingertapping task:<br>target score (total number of correct responses), execution time (time required to the subsequent correct response in ms)