To study the efficacy of low dose oral minoxidil versus 5% topical minoxidil versus 5% topical minoxidil and Platelet rich plasma procedure combination in patients with androgenetic alopecia
Not Applicable
- Conditions
- Health Condition 1: L648- Other androgenic alopecia
- Registration Number
- CTRI/2023/05/052909
- Lead Sponsor
- Self
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All androgenetic alopecia patients from Norwood Hamilton grade 3-5 are recruited.
Exclusion Criteria
Patients suffering from other hair disorders, hypotensive episodes, irritant dermatitis to minoxidil, keloidal tendency and bleeding disorders
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients showing improvement in modified Norwood-Hamilton scale by 1 grade in each group at end of 24 weeksTimepoint: assessed at baseline, 4th month, 6th month
- Secondary Outcome Measures
Name Time Method Videodermoscopic assessment as proportion of patients showing 25% increase in hair density 25% decrease in hair diameter diversity and 25% decrease in number of vellus hair/mm2 by end of 24 weeks. Change in population of natural (CD25 high) and induced (CD25 low) T reg cells using Fluorescent activated cell sorting change in NOTCH pathway jagged 1 SOX 9 expression in hair follicle using immunofluorescence pre and post treatmentTimepoint: assessment done at baseline, 16 weeks and 24 weeks