Canadian Anticoagulant Percutaneous Coronary Intervention Registry

Completed

• Conditions: Coronary Artery Disease

• Registration Number: NCT00773006
• Lead Sponsor: University of Alberta

Brief Summary

Advances in mechanical intervention (PCI) and anticoagulation therapy have been the cornerstone of treatment of patients with coronary artery disease. However, the large diversity of approaches to anticoagulation during PCI introduces gaps in knowledge regarding management of cardiac patients. As such, we have initiated a national PCI registry to elucidate anticoagulant choice, dosing strategies, case selection dynamics, and clinical outcomes in the Canadian health care environment.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2008-01-28
• Study Start: 2008-02
• Study First Submitted QC: 2008-10-15
• Study First Posted: 2008-10-16
• Primary Completion: 2010-06
• Study Completion: 2011-09
• Status Verified: 2011-10
• Last Update Submitted: 2011-10-03
• Last Update Posted: 2011-10-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 747

Inclusion Criteria

1. 18 or more years of age.
2. Undergoing PCI during treatment with LMWH
3. Provision of written and informed consent

Exclusion Criteria

1. Language, medical, or psychiatric barriers that preclude understanding of informed consent process.
2. Patients in which the site investigator is unable to comply with completion of study documentation following PCI, i.e. patients with planned transfer to another hospital not participating in the registry.
3. Enrollment in a clinical trial involving another anticoagulant agent.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Description of anticoagulant management during PCI and current practices of participating centres will be undertaken	in-hospital

Secondary Outcome Measures

Name	Time	Method
In-hospital safety outcomes including - major, minor bleeding, requirement for transfusion, death, myocardial infarction (or re-MI), myocardial ischemia requiring urgent revascularization, and major bleeding	in-hospital
PCI-related resources utilization during the study period, including cost of PCI and its treatment (e.g. duration of hospital stay, drug costs, costs related to bleeding such as transfusions)	in-hospital
In-hospital angiographic complications: no reflow, thrombus, occlusion of collateral branches, distal embolism, coronary dissection, acute closure of the culprit vessel	in-hospital

Trial Locations

Locations (1)

University of Alberta; 🇨🇦 Edmonton, Alberta, Canada