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临床试验/CTRI/2025/10/096072
CTRI/2025/10/096072尚未招募不适用

A comparative observational study to assess the effect of ketamine and dexamethasone for endotracheal tube cuff inflation on post-operative sore throat, cough and hoarseness of voice

Peoples Hospital1 个研究点 分布在 1 个国家目标入组 180 人开始时间: 2025年11月3日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
180
试验地点
1
主要终点
Incidence and severity of post operative sore throat cough hoarseness of voice

研究概览

简要总结

Patients posted for elective surgeries under general anesthesia will be placed in 2 groups. For patients under group K the endotracheal tube cuff will be inflated with inj. ketamine 0.4 mg per kg diluted in 5ml NS and for the patients under group D the endotracheal  tube cuff will be inflated with inj. dexamethsone 0.1 per kg diluted in 5ml NS. Post operatively patients will be assessed at 1,6,24 hours for post operative sore throat, cough and hoarseness of voice

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients willing to give informed consent ASA grade I and II Patients posted for elective surgeries under general anaesthesia with endotracheal tube intubation lasting for more than 2 hours.

排除标准

  • Patients not giving informed consent ASA grade more than III History of postoperative sore throat History of asthma or chronic obstructive disease Patients who require more than 1 attempt for intubation.

结局指标

主要结局

Incidence and severity of post operative sore throat cough hoarseness of voice

时间窗: 24 hours

次要结局

未报告次要终点

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Ruchi Shadija

Peoples College of Medical Sciences and Research Centre

研究点 (1)

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