CTRI/2025/10/096072尚未招募不适用
A comparative observational study to assess the effect of ketamine and dexamethasone for endotracheal tube cuff inflation on post-operative sore throat, cough and hoarseness of voice
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Incidence and severity of post operative sore throat cough hoarseness of voice
研究概览
简要总结
Patients posted for elective surgeries under general anesthesia will be placed in 2 groups. For patients under group K the endotracheal tube cuff will be inflated with inj. ketamine 0.4 mg per kg diluted in 5ml NS and for the patients under group D the endotracheal tube cuff will be inflated with inj. dexamethsone 0.1 per kg diluted in 5ml NS. Post operatively patients will be assessed at 1,6,24 hours for post operative sore throat, cough and hoarseness of voice
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients willing to give informed consent ASA grade I and II Patients posted for elective surgeries under general anaesthesia with endotracheal tube intubation lasting for more than 2 hours.
排除标准
- •Patients not giving informed consent ASA grade more than III History of postoperative sore throat History of asthma or chronic obstructive disease Patients who require more than 1 attempt for intubation.
结局指标
主要结局
Incidence and severity of post operative sore throat cough hoarseness of voice
时间窗: 24 hours
次要结局
未报告次要终点
研究者
Dr Ruchi Shadija
Peoples College of Medical Sciences and Research Centre
研究点 (1)
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