Intravenous Metoprolol Versus Intravenous Amiodarone in the Prevention of Atrial Fibrillation After Cardiac Surgery

Phase 4

Completed

• Conditions: Atrial Fibrillation; Cardiac Surgery
• Interventions: Drug: metoprolol, amiodarone

• Registration Number: NCT00784316
• Lead Sponsor: Kuopio University Hospital

Brief Summary

The aim of the study is to test the efficiency of intravenous administration of metoprolol versus intravenous administration of amiodarone in the prevention of atrial fibrillation after cardiac surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08
• Study First Submitted: 2008-10-31
• Study First Submitted QC: 2008-10-31
• Study First Posted: 2008-11-02
• Primary Completion: 2009-07
• Study Completion: 2009-07
• Status Verified: 2011-11
• Last Update Submitted: 2011-11-23
• Last Update Posted: 2011-11-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 316

Inclusion Criteria

• elective CABG and aortic valve patients in cardiac surgery,
• previous use of betablocker therapy

Exclusion Criteria

• previous atrial fibrillation or flutter,
• thyroid disease,
• uncontrolled heart failure,
• II or III degree atrioventricular block

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
metoprolol	metoprolol, amiodarone	-
amiodarone	metoprolol, amiodarone	-

Primary Outcome Measures

Name	Time	Method
Incidence of atrial fibrillation	48 hours

Trial Locations

Locations (1)

Halonen jari; 🇫🇮 Kuopio, Finland