The Effect of a Predictive Model of Bowel Preparation Based on Procedure-related Factors: a Multicenter, Randomized Controlled Study
Overview
- Phase
- Not Applicable
- Intervention
- Polyethylene glycol
- Conditions
- Colonoscopy
- Sponsor
- Air Force Military Medical University, China
- Enrollment
- 900
- Locations
- 5
- Primary Endpoint
- Adequate bowel preparation
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The rate of adequate bowel preparation is one of important quality indicators of colonoscopy. Inadequate bowel preparation negatively affects the outcomes of colonoscopy. If patients with inadequate bowel preparation were identified before the procedure, enhanced strategy could be offered to achieve better bowel cleaning. Currently, there were three predicting models of inadequate bowel preparation established based on patient-related factors. So far, none of predictive models have been tested in other than their validation cohort populations, and no study has attempted to apply a different regimen to patients presenting with risk factors for inadequate colon cleanliness. In previous studies, we established a prediction model based on procedure-related factors, which has better accuracy and can better predict the quality of bowel preparation.
The aim of this study is to compare the quality of bowel preparation by using a predictive model based on procedure-related factors versus the criterion group in unsedation patients
Investigators
Yanglin Pan
Associated professor
Air Force Military Medical University, China
Eligibility Criteria
Inclusion Criteria
- •Age: 18\~75 years
- •Patients undergoing morning colonoscopy
Exclusion Criteria
- •colon resection;
- •suspected bowel obstruction;
- •moderate or severe complications related to drinking the 1st or 2rd dose of PEG
- •hemodynamically unstable;
- •lactating or pregnant women;
- •no need to reach the ileocecal segment
- •unwilling to provided informed content.
Arms & Interventions
model-based interference group
Patients with score ≥3 were asked to taking another dose of PEG (1.5L) within 1-2 hours. Colonoscopy was performed in afternoon (about 4h after drinking PEG). Patients with score\<3 in IM group colonoscopy directly.
Intervention: Polyethylene glycol
Outcomes
Primary Outcomes
Adequate bowel preparation
Time Frame: 6 months
Defined by each segmental BBPS≥2
Secondary Outcomes
- Overall complication related to bowel preparation(6 months)
- Adenoma detection rate(6 months)