NCT01474629已完成不适用
Impact of Supplementation With Probiotics on Exercise-induced Oxidative Stress and Endotoxemia in Trained Men
Green Beat2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2011年10月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- markers of oxidative stress, endotoxemia and inflammation
研究概览
简要总结
We investigate the impact of a probiotic-based dietary supplement on oxidative stress and endotoxemia before and after strenuous exercise.
Hypotheses (H1):
- Supplementation has an influence on oxidative stress parameters before and post exercise
- Supplementation has an influence on parameters of endotoxemia and inflammation before and post exercise
- Strenuous exercise has an influence on parameters of oxidative stress, inflammation and endotoxemia
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 30 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •trained men
- •30 - 45 years
- •non-smokers
- •4wk wash out of all dietary supplements
排除标准
- •untrained people (VO2max < 55 ml x kg-1)
- •all people not matching this age group
- •all men taking dietary supplements
- •all men that fail in ergometric exercise eligibility testing, refering to the standards in sports medicine (e.g.: significant ST-decrease or increase, blood pressure > 240 mmHg, tachycardia, polymorphic extrasystolia, cyanosis, bradyarrhythmia..)
- •all people that are not adjudged as "Healthy"
结局指标
主要结局
markers of oxidative stress, endotoxemia and inflammation
时间窗: 6 months
次要结局
未报告次要终点
研究者
Lamprecht Manfred PhD, PhD
Principal investigator
Green Beat
研究点 (2)
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