A comparison of nebulized 3% hypertonic saline and epinephrine versus nebulized normal saline and epinephrine in the treatment of acute bronchiolitis

Completed

• Conditions: Bronchiolitis; Respiratory

• Registration Number: ISRCTN66632312
• Lead Sponsor: niversity of Alberta, Department of Pediatrics (Canada)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-13
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 46

Inclusion Criteria

Infants 6 weeks to 12 months of age with clinical symptoms of a viral respiratory infection (coryza or temperature = 38.0°C), first episode of wheezing, oxygen saturation = 85% but = 96%, and initial Respiratory Distress Assessment Instrument (RDAI) score = 4.

Exclusion Criteria

Pre-existing cardiac or pulmonary disease, previous diagnosis of asthma by a physician, any previous use of bronchodilators, severe disease requiring resuscitation room care, inability to administer medication by nebulizer, inability to obtain informed consent secondary to a language barrier, or no phone access for follow-up.

Study & Design

• Study Type: Interventional
• Study Design: Not specified