Effect of Time Delay and Syringe Surface Area on Blood Gas Samples Analysis

Completed

• Conditions: Respiratory Failure

• Registration Number: NCT06522009
• Lead Sponsor: Helwan University

Brief Summary

To detect the effect of time delay and syringe surface area on the oxygen tension (PaO2), oxyhaemoglobin saturation (SaO2), acidity (pH), and carbon dioxide tension (PaCO2) in both arterial and venous blood gas outcomes.

Detailed Description

Arterial blood gas (ABG) analysis and monitoring is a crucial process for the diagnosis and management of the oxygenation status and acid-base balance of high-risk patients during surgery, as well as for the critical care of critically ill patients in the Intensive Care Unit .

Acid-base imbalance anomalies can have major repercussions in a number of medical scenarios, and in a few rare instances, they may even be a risk factor for death.

ABG test explores the arterial blood's pH, oxyhaemoglobin saturation (SaO2), bicarbonate concentration (HCO3), oxygen tension (PaO2), and carbon dioxide tension (PaCO2).

Traditionally, the concept "blood gas testing" has been used to describe measuring the blood's pH, oxygen saturation of haemoglobin (SaO2), and partial pressures of the physiologically active gases (pO2, pCO2). But now available commercial equipment can measure electrolytes (sodium, potassium, chloride, ionized calcium, and magnesium), glucose, lactate, and creatinine, usually all at the same time, in addition to haemoglobin quantification and co-oximetry

Study Timeline

• Study Start: 2019-07-30
• Primary Completion: 2020-07-30
• Study Completion: 2020-07-30
• Study First Submitted: 2024-07-18
• Study First Submitted QC: 2024-07-23
• Study First Posted: 2024-07-26
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-07
• Last Update Posted: 2024-08-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Critically ill-patients, and intraoperative patients who aged above 18 years.

Exclusion Criteria

• Patients with haematological diseases e.g. sickle cell anaemia
• burn patients with risk of carbon monoxide poisoning
• ARDS
• pulmonary oedema
• samples that were clotted

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To detect the effect of time delay and syringe surface area on the oxygen tension (PaO2) arterial and venous blood gas outcomes.	1 hour	PaO2 by mmhg arterial and venous samples; To detect the effect of time delay and syringe surface area on SO2 in arterial and venous samples; To detect the effect of time delay and syringe surface area on other parameters of blood gases e.g. PH,CO2

Secondary Outcome Measures

Name	Time	Method
effect of delay on analysis oxyhaemoglobin saturation (SaO2) acidity (pH) carbon dioxide tension (PaCO2)	60 minutes	spao2 by mmhg and paco2 by mmhg

Trial Locations

Locations (1)

Theodor Bilharz Research Institute; 🇪🇬 Cairo, Egypt