Jiangsu Provincial Hospital of Traditional Chinese Medicine
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- Childhood Autism Rating Scale
研究概览
简要总结
Using the knowledge graph and big model technology of combining Chinese and Western medicine we construct a popularization and prevention system for childhood encephalopathy an assisted decision-making system for childhood encephalopathy and a follow-up tracking question and answer system for childhood encephalopathy patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 2 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •meet diagnostic criteria for CP ID TD ADHD ASD;
- •gender is not limited;
排除标准
- •CP ID TD ASD due to chorea hepatomegaly hearing abnormality and pharmacogenetic factors;
- •Children with other major mental illnesses (e.g. schizophrenia) or organic diseases (e.g. congenital heart disease);
结局指标
主要结局
Childhood Autism Rating Scale
时间窗: 4 mouths
The total score ranges from 15 to 60, with the higher the score the worse the symptoms are
meridian and acupointological features
时间窗: 4 mouths
After obtaining the information through diagnosis by a professional Chinese medicine practitioner, assist in the diagnosis of clinical subtypes of children according to the corresponding typology of "Pediatrics of Chinese Medicine".
Yale Global Tic Severity Scale
时间窗: 4 mouths
It has a score range of 0-100, with higher scores representing more severe symptoms.
Gross Motor Function Assessment Scale (GMFM)-88
时间窗: 4 mouths
GMFM-88 scores range from 0-264, with higher scores being better.
Autism Behavior Checklist
时间窗: 4 mouths
It has a score range of 0-174, with higher scores representing more severe symptoms.
acupuncture point status
时间窗: 4 mouths
After obtaining the information through diagnosis by a professional Chinese medicine practitioner, assist in the diagnosis of clinical subtypes of children according to the corresponding typology of "Pediatrics of Chinese Medicine".
Tongue texture
时间窗: 4 mouths
After obtaining the information through diagnosis by a professional Chinese medicine practitioner, assist in the diagnosis of clinical subtypes of children according to the corresponding typology of "Pediatrics of Chinese Medicine".
Wechsler intelligence scale (WIS)
时间窗: 4 mouths
FIQ = 100: Indicates that the individual has an average level of intelligence. FIQ \> 100: Indicates an above average level of intelligence. FIQ \< 100: Indicates a below average level of intelligence.
Resting heart rate
时间窗: 4 mouths
blood pressure (systolic, diastolic) after 10 minutes of rest
时间窗: 4 mouths
Conners Rating Scales
时间窗: 4 mouths
Scores are converted to standardized T-scores for comparison with the mean of the peer group. T-scores above 65 are usually considered clinically significant.
tongue coating, pulse
时间窗: 4 mouths
After obtaining the information through diagnosis by a professional Chinese medicine practitioner, assist in the diagnosis of clinical subtypes of children according to the corresponding typology of "Pediatrics of Chinese Medicine".
respiratory rate
时间窗: 4 mouths
Body temperature
时间窗: 4 mouths
次要结局
- Saliva(4 mouths)
- blood(4 mouths)
- Urine(4 mouths)
- Faeces(4 mouths)
研究者
Yun Liu,PhD
PhD
Affiliated Hospital of Nanjing University of Chinese Medicine