Selective Nerve Root Block With Ultrasound Guidance Improves Surgical Outcome of Selective Discectomy in Patients With Multilevel Cervical Disc Disease

Phase 2

Completed

• Conditions: Selective Discectomy; Selective Nerve Root Block
• Interventions: Procedure: selective anterior cervical discectomy and fusion (ACDF); Procedure: SNRB+ selective anterior cervical discectomy and fusion (ACDF)

• Registration Number: NCT05145530
• Lead Sponsor: Assiut University

Brief Summary

Disc degeneration is a natural part of growing older. Up to 60% of asymptomatic people have MRI findings that are positive. As a result, MRI only provides morphological information and may not be able to determine the clinical significance of the findings.

Detailed Description

Many authors believe that patients who suffer from cervical radiculopathy as a result of degenerative disease and have multilevel pathology on imaging studies still have moderate surgical outcomes. This occurs due to a misdiagnosis or the need to perform surgery on multiple levels despite a single painful lesion.

Although the complication rate for 1- and 2-level ACDF is so low that it is considered one of the safest procedures in spine surgery. There is concern that increasing levels of fusion will lead to more complications, such as a higher incidence of persistent axial neck pain, dysphagia, and vertebral artery injury, as well as more postoperative pain and higher narcotic dosages.

Study Timeline

• Study Start: 2017-08-10
• Primary Completion: 2020-03-30
• Study Completion: 2020-04-30
• Study First Submitted: 2021-11-26
• Status Verified: 2021-12
• Study First Submitted QC: 2021-12-03
• Study First Posted: 2021-12-06
• Last Update Submitted: 2021-12-15
• Last Update Posted: 2022-01-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• all patients presented with unilateral brachialgia due to multilevel cervical disc disease

Exclusion Criteria

• multilevel cervical disc disease who had bilateral brachialgia,
• myelopathy, double crush syndrome,
• ossified posterior longitudinal ligament (OPLL),
• combined anterior and posterior pathology requiring posterior decompression

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group C	selective anterior cervical discectomy and fusion (ACDF)	selective anterior cervical discectomy and fusion (ACDF)
Group SNRB	SNRB+ selective anterior cervical discectomy and fusion (ACDF)	US-guided selective nerve root block (SNRB) then selective anterior cervical discectomy and fusion (ACDF)

Primary Outcome Measures

Name	Time	Method
pain intensity	24 hours postoperative	Visual analogue score (VAS): 0= no pain, 10= worst pain

Trial Locations

Locations (1)

Assiut governorate; 🇪🇬 Assiut, Egypt