Efficacy of ramosetron for prevention of postoperative nausea and vomiting in patients after total knee arthroplasty according to time of administration.
Not Applicable
Recruiting
- Conditions
- Diseases of the musculo-skeletal system and connective tissue
- Registration Number
- KCT0005080
- Lead Sponsor
- Seoul Metropolitan Government Seoul National University Boramae Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
the patients who underwent primary total knee arthroplasty due to end-stage osteoarthritis
Exclusion Criteria
contraindication to spinal anesthesia or conversion to general anesthesia due to failure of spinal anesthesia
patients undergoing total knee arthroplasty, not due to osteoarthritis
revision total knee arthroplasty
patients undergoing bilateral total knee arthroplasty, 2nd surgery of staged total knee arthroplasty
patients with an allergy to 5-HT3 receptor antagonists
history of using streoid or other antiemetic drugs within 24 hours before surgery
in the case of patient's medical condition which prevent using ramosetron
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method nausea;vomiting
- Secondary Outcome Measures
Name Time Method rescue antiemetics;complication such as headache, dizziness, dorwsiness