Investigation of Clot in Ischemic Stroke and Hematoma Evacuation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 400
- 试验地点
- 27
- 主要终点
- Blood and Clot Specimen Transcriptomics
研究概览
简要总结
The aim of the study is to collect and analyze specimen from ischemic stroke patients undergoing thrombectomy procedures and from patients undergoing minimally invasive surgery for intracranial hematoma evacuation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥ 18 Years of Age
- •Frontline treatment with: Penumbra System for ischemic stroke patients eligible for mechanical thrombectomy or Artemis Neuro Evacuation device for intracranial hematoma evacuation in patients eligible for minimally invasive surgery (MIS)
- •Extracted thrombus/embolus
- •Informed consent is obtained from either the patient or legally authorized representative (LAR)
排除标准
- •Pregnancy or positive pregnancy test according to site routine practice (only required for women of child bearing potential; serum or urine acceptable)
- •Currently participating in an investigational drug or device clinical trial that may confound the ability to capture clot and/or influence clot composition. Patients in observational, natural history, and/or epidemiological studies not involving intervention are eligible
结局指标
主要结局
Blood and Clot Specimen Transcriptomics
时间窗: Blood and clot specimen obtained during procedure
Numbers of blood and clot for RNA sequency. Only includes successful sample number that was processed.
Blood and Clot Specimen Proteomics
时间窗: Blood and clot specimen obtained during procedure
Numbers of blood and clot specimen for proteomic analysis
Clot Specimen Histology
时间窗: Clot specimen obtained during procedure
Numbers of clot specimen for histology analysis
Blood and Clot Specimen Genomics
时间窗: Blood and clot specimen obtained during procedure
Numbers of blood and clot specimen for single nucleotide polymorphisms (SNPs). Only includes successful sample number that was processed.
次要结局
未报告次要终点