A Study to assess role of 18F-FDG PET-CT immediately after PAMI in a case of coronary artery disease
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Improvement of Ejection fraction and reperfusion
研究概览
简要总结
This prospective observational study will evaluate the role
of 18F-FDG PET-CT in detecting myocardial inflammation
immediately after Percutaneous Angioplasty with
Myocardial Intervention (PAMi) in patients with coronary
artery disease. PET-CT will be performed within 24–72
hours post-procedure and repeated at 3–6 months to assess
changes in myocardial metabolic activity.
The study aims to correlate early FDG uptake with ejection
fraction, serum biomarkers, procedural details, and short-
term outcomes such as recurrent angina or
rehospitalization. It is hypothesized that early PET-CT can
identify inflammation reflecting procedural impact and
predict recovery, with follow-up scans showing reperfusion
and improvement in cardiac function.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients who qualify for a need of diagnostic angiography followed by angioplasty
- •Acute ST-elevation myocardial infarction
- •Non ST-elevation myocardial infarction
- •Unstable angina
- •Stable angina
- •Anginal equivalent
- •High risk stress test findings.
排除标准
- •un willing for 18F-FDG PET-CT Pregnant women Psychiatry patients claustrophobic.
结局指标
主要结局
Improvement of Ejection fraction and reperfusion
时间窗: Improvement of Ejection fraction and reperfusion
次要结局
- To check for improvement in ejection fraction and reperfusion.(To correlate FDG uptake with procedural details (number of vessels involved, stent placement, and duration).)
研究者
Dr Vigneshwaran M
INHS Asvini