The Role of Transversus Abdominis Plane Block and Rectus Sheath Block in Reduction of Postoperative Pain for Gynecological Benign Surgical Laparoscopic Procedures: a Randomized Controlled Trial
Overview
- Phase
- Phase 2
- Intervention
- TAP block and RS block + General Intravenous Anesthestic
- Conditions
- TAP and RS Block
- Sponsor
- Campus Bio-Medico University
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- analgesic consumption in the first 72 hours after gynecological surgical procedures
- Last Updated
- 7 years ago
Overview
Brief Summary
The present study aims to demonstrate the effectiveness of loco-regional wall anesthesia of the transversus abdominis plane block (TAP block) and the rectus sheath block (RS block), compared to intravenous analgesia, in terms of pain reduction, postoperative analgesic drugs consumption, patient satisfaction and decrease of LOS (length of stay), in patients undergoing benign gynecological laparoscopic surgical procedures.
Investigators
Corrado Terranova
Principal Investigator
Campus Bio-Medico University
Eligibility Criteria
Inclusion Criteria
- •patients undergoing benign laparoscopic gynecological surgery
- •age between 18 and 75 years
- •BMI \>18 e \<35
- •ECOG Performance Status 0-1
Exclusion Criteria
- •age \< 18 or \> 75 years
- •BMI \<18 or \> 35
- •ECOG Performance Status \>1
- •Allergy to local anesthetics
- •Allergy to NSAIDs
- •Chronic kidney failure \> II class
- •Systemic neoplastic disease actual or previous
- •Actual pregnancy
- •Active or recent pelvic inflammation
- •Persistent coagulopathy
Arms & Interventions
ALR
Intervention: TAP block and RS block + General Intravenous Anesthestic
EV
Intervention: General Intravenous Anesthetic
Outcomes
Primary Outcomes
analgesic consumption in the first 72 hours after gynecological surgical procedures
Time Frame: analgesic consumption in the first 72 hours after gynecological surgical procedures
analgesic consumption in the first 72 hours after gynecological surgical procedures
postoperative pain in the first 72 hours after gynecological surgical procedures
Time Frame: postoperative pain in the first 72 hours after gynecological surgical procedures
postoperative pain in the first 72 hours after gynecological surgical procedures