Effect of Drinking Carbohydrate-containing Fluids on Gastric Residual Volume in Elderly Patients

Completed

• Conditions: Fasting
• Interventions: Other: Non-carbohydrate fluid; Other: Carbohydrate fluid

• Registration Number: NCT04514380
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

In the past, some guidelines advised no oral intake for at least 8 hours before any surgery. However, research has shown risks associated with excessive fasting, such as postoperative insulin resistance, and advantages in shorter fasting protocols, such as reduced postoperative nausea and vomiting.

The perioperative fasting guidelines of the European Society of Anaesthesiology focus on preoperative carbohydrates. They hold that it is safe for patients to drink carbohydrate-rich fluids up to 2 hours before elective surgery and that drinking carbohydrate-rich fluids improves subjective well-being, reduces thirst and hunger, and reduces postoperative insulin resistance at an evidence level of 1++. Nevertheless, data on drinking carbohydrate fluids before surgery in elderly patients are limited.

In our institution, there are two clinical pathways for total knee arthroplasty according to the surgeons. One difference is whether carbohydrate fluids drink or not before surgery. The purpose of this study, therefore, is to assess gastric volume in fasted elderly patients using ultrasound after they drank carbohydrate fluids 2 hours before surgery and to compare with matched patients using age, body mass index, and comorbidity, who did not drink carbohydrate fluids before surgery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-08-12
• Study First Submitted QC: 2020-08-12
• Study First Posted: 2020-08-14
• Study Start: 2020-09-16
• Status Verified: 2021-03
• Primary Completion: 2021-03-19
• Study Completion: 2021-03-19
• Last Update Submitted: 2021-03-19
• Last Update Posted: 2021-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• Patients undergoing total knee arthroplasty
• Age: 65~85 yeas
• ASA 1~3

Exclusion Criteria

• Age < 65 years
• ASA >= 4
• Diabetes mellitus
• Chronic kidney disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group N	Non-carbohydrate fluid	Patients did not drink carbohydrate fluid 2 hours prior to surgery according to the routine fasting protocol by surgeon B.
Group C	Carbohydrate fluid	Patients drank carbohydrate fluid 2 hours prior to surgery according to the routine fasting protocol by surgeon A.

Primary Outcome Measures

Name	Time	Method
Gastric volume	During the gastric volume measuring at preoperative holding area/ an average of 30 minutes	Gastric volume measured before induction of spinal anesthesia using ultrasound

Trial Locations

Locations (1)

Seoul National Univ. Bundang Hospital; 🇰🇷 Seongnam, Gyeonggi, Korea, Republic of