NCT01265147Unknown2 期
Phase II Study to Evaluate Efficacy and Safety of Intensity-modulated Radiation Therapy Combined With Cisplatin or Nedaplatin Chemotherapy in Patients With Nasopharyngeal Carcinoma
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2011年1月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- locoregionally control rate
研究概览
简要总结
This phase II trial is studying cisplatin or nedaplatin combine with IMRT to evaluate which one is better efficacy and security in nasopharyngeal carcinoma.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age≥18,T1-2aN1-3;T2-4NxNPC,VEGFR+,++,KPS>70,Life expectancy≥6 months, No uncontrolled hypertension,cardiac failure,diabetes,lunacy
排除标准
- •Distant metastasis, recurrent disease
研究组 & 干预措施
Cisplatin
Active Comparator
cisplatin combine with IMRT
干预措施: Cisplatin (Drug)
Nedaplatin
Experimental
Nedaplatin combine with IMRT
干预措施: Nedaplatin (Drug)
结局指标
主要结局
locoregionally control rate
时间窗: 3 months
3 months after treatment
次要结局
- Survival(1,3,5 years)
研究者
研究点 (1)
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