ProspEctive Randomized First Evaluation in Chest Pain Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 411
- 试验地点
- 1
- 主要终点
- Change in medical regimen
研究概览
简要总结
The purpose of this study is to determine the best initial test in patients admitted to the hospital complaining of chest pain.
详细描述
Currently, physicians can either choose a stress test or a CT scan of the heart to evaluate patients admitted with with chest pain. Very little is known about which test provides the best information to physicians, positively impacts patients medical care, and decreases future hospital admissions and testing. To study this the investigators are randomizing patients admitted to our hospital with chest pain to a stress test or coronary CT angiography. The investigators will then follow these patients for a 2 year period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with chest pain or SOB admitted for rule out acute coronary syndrome
- •Age ≥45 years
- •EKG non-diagnostic for acute coronary syndrome
- •At least 1 set of negative troponin I
排除标准
- •Patient with ST elevation myocardial infarction.
- •Patients with non-ST elevation myocardial infarction.
- •Patients with known CAD.
- •Patients with serum creatinine > 1.
- •Atrial fibrillation or marked irregular heart rhythm.
- •Patients in whom heart rate cannot be controlled.
- •Patient with allergies to iodinated contrast agents.
- •Pregnant women
- •Patients unable to give informed consent
结局指标
主要结局
Change in medical regimen
时间窗: Initial hospitalization
Downstream cardiovascular testing and hospitalization
时间窗: 2 years
Time to discharge
时间窗: Initial hospitalization
次要结局
- Cardiovascular mortality(7 days, 30 days, 6, 12, and 24 months.)
- Non-fatal myocardial infarction(7 days, 30 days, 6, 12, and 24 months.)
- All-cause mortality(7 days, 30 days, 6, 12, and 24 months.)