Hepatitis C Reinfection in an Injection Drug Using Population in Kenya: A Follow-up to the TLC-IDU Hepatitis C V Supplement Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 101
- 试验地点
- 1
- 主要终点
- Examine usage of needle exchange programs
研究概览
简要总结
The goal of this research project is to build upon the Testing and Linkage to Care for Injecting Drug Users (TLC-IDU) parent study and describe post-cure HCV reinfection in a population of people who inject drugs (PWIDs) in Kenya.
详细描述
In addition to describing reinfection in a substance using cohort, we will identify individual predictors of HCV reinfection in Kenya, as well as identifying individual utilization intervention approaches and dosing that reduce reinfection risk and treatment cite level risk factors (frequency of visits, community vs hospital location etc.). Determining the risk factors specific to reinfection and understanding the impact of concurrent harm reduction interventions will guide service delivery and implementation of HCV elimination strategies in Kenya and throughout the region.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Live in Nairobi or coastal Mombasa (Coast Province including Malindi), Kenya;
- •Are injection drug users (IDUs) that ever injected any non-prescribed drugs; and able and willing to provide informed consent.
- •Participates are in the parent study;
- •Complete treatment protocol; and achieve a sustained virologic response (SVR).
排除标准
- •Not in the above inclusion criteria.
结局指标
主要结局
Examine usage of needle exchange programs
时间窗: 12 months
Brief questionnaire on services used
Evaluate psychoeducational counseling
时间窗: 12 months
Brief questionnaire on knowledge, attitude and beliefs of each participant.
HCV Reinfection
时间窗: 6-18 months post sustained virologic response (SVR) to HCV treatment.
The reinfection of patients with hepatitis C after completion of a previous HCV infection treatment.
Examine usage of methadone maintenance
时间窗: 12 months
Brief questionnaire on services used
次要结局
- HCV reinfection referrals for treatment at Kenyetta National Hospital(9-16 months post treatment)