跳至主要内容
临床试验/NL-OMON24867
NL-OMON24867招募中不适用

Dendritic-cell-based immunotherapy combined with low-dose cyclophosphamide in patients with malignant pleural mesothelioma.

Erasmus Medical CenterDepartment of Pulmonary MedicineRotterdam0 个研究点目标入组 10 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
10

研究概览

简要总结

Hegmans JP, Hemmes A, Aerts JG, Hoogsteden HC, Lambrecht BN. Immunotherapy of murine malignant mesothelioma using tumor lysate-pulsed dendritic cells. Am J Respir Crit Care Med 2005; 171:1168-77.

Hegmans JP, Hemmes A, Hammad H, Boon L, Hoogsteden HC, Lambrecht BN. Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responses. Eur Respir J 2006; 27:1086-95.

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1. Patients with clinically and histological or cytological confirmed newly diagnosed MM, that can be measured in two dimensions by a radiologic imaging study;
  • 2. Patients must be at least 18 years old and must be able to give written informed consent;

排除标准

  • 1. Conditions that make the patient unfit for chemotherapy or progressive disease after 4 cycles of chemotherapy;
  • 2. Pleurodesis at the affected side before the pleural fluid is obtained;

研究者

发起方
Erasmus Medical CenterDepartment of Pulmonary MedicineRotterdam

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