NL-OMON24867招募中不适用
Dendritic-cell-based immunotherapy combined with low-dose cyclophosphamide in patients with malignant pleural mesothelioma.
Erasmus Medical CenterDepartment of Pulmonary MedicineRotterdam0 个研究点目标入组 10 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 10
研究概览
简要总结
Hegmans JP, Hemmes A, Aerts JG, Hoogsteden HC, Lambrecht BN. Immunotherapy of murine malignant mesothelioma using tumor lysate-pulsed dendritic cells. Am J Respir Crit Care Med 2005; 171:1168-77.
Hegmans JP, Hemmes A, Hammad H, Boon L, Hoogsteden HC, Lambrecht BN. Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responses. Eur Respir J 2006; 27:1086-95.
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Patients with clinically and histological or cytological confirmed newly diagnosed MM, that can be measured in two dimensions by a radiologic imaging study;
- •2. Patients must be at least 18 years old and must be able to give written informed consent;
排除标准
- •1. Conditions that make the patient unfit for chemotherapy or progressive disease after 4 cycles of chemotherapy;
- •2. Pleurodesis at the affected side before the pleural fluid is obtained;
研究者
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