A Clinical Study on the Improvement of Unstable carotid plaque by Yiqi Tongluo Decoction Based on Inflammatory Factors

Not Applicable

• Conditions: nstable carotid plaque

• Registration Number: ITMCTR2000003946
• Lead Sponsor: Shanghai Municipal Hospital of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Agree to accept this clinical trial, which meets the diagnostic criteria of ultrasound imaging of carotid artery unstable plaque; meets the diagnostic criteria of TCM Qi deficiency and phlegm stasis syndrome; age 45 years or older; have not taken other traditional Chinese medicines or proprietary Chinese medicines, or have stopped taking medicine for more than 4 weeks; Those who have not received other trials within 3 months.

Exclusion Criteria

(1) Grade 4 cardiac function or pulmonary edema;
(2) Severe primary brain and lung diseases and liver and kidney dysfunction;
(3) Allergic to traditional Chinese medicine;
(4) Patients with malignant diseases;
(5) Severe inflammatory disease;
(6) patients with bleeding diseases;
(7) malignant arrhythmia;
(8) acute coronary syndrome;
(9) Mental patients;
(10) Pregnant or nursing women;
(11) Those who participated in other clinical trials within the past month.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
tumornecrosisfactor-alpha (TNF-alpha);Carotid artery area;interleukin-6 (IL-6);Carotid intima-media thickness (IMT);hypersensitiveC-reactiveprotein, (hs-CRP);

Secondary Outcome Measures

Name	Time	Method
Major cardiovascular events;The quality of life;Clinical symptoms;