A Clinical Study on the Effect of Oliceridine（TRV130） on Postoperative Rebound Pain and Early Rehabilitation Exercise After Knee Arthroscopy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 320
- 试验地点
- 1
- 主要终点
- The degree of the rebound pain
研究概览
简要总结
The purpose of this clinical study was to identify the risk factors for postoperative pain outburst in patients undergoing arthroscopic knee surgery after Oliceridine and nerve block, and to evaluate the effect of oxeridine on early rehabilitation exercise in patients. A total of 320 patients undergoing arthroscopic knee arthroscopy under general anesthesia combined with femoral nerve block were selected to record the time and duration of postoperative pain outbreak, pain degree, age, gender, operation type, previous surgical history and other related risk factors.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-70 years old;
- •Body mass index (BMI) 18-30kg /m2;
- •American Society of Anesthesiologists (ASA) Grade I to II;
- •Hospital stay >24h.
排除标准
- •Patients who cannot understand the numerical rating scale score and give feedback;
- •Known allergy to the drug in the study;
- •Infection of puncture site with nerve block;
- •Oral analgesics for more than 2 weeks before surgery;
- •Long-term use of glucocorticoids;
- •Simultaneous surgery on both limbs;
- •A psychopath;
- •Severe compound trauma;
- •Pregnant and lactating women.
结局指标
主要结局
The degree of the rebound pain
时间窗: Within 48 hours after surgery
The numerical rating scale was used
Previous surgical history
时间窗: Within 48 hours after surgery
Fill in the postoperative questionnaire
Time of onset of postoperative rebound pain
时间窗: Within 48 hours after surgery
The numerical rating scale was used
The duration of the rebound pain
时间窗: Within 48 hours after surgery
The numerical rating scale was used
age
时间窗: Within 48 hours after surgery
Fill in the postoperative questionnaire
sex
时间窗: Within 48 hours after surgery
Fill in the postoperative questionnaire
Surgical procedure
时间窗: Within 48 hours after surgery
Fill in the postoperative questionnaire
次要结局
- Movement recovery time(Within 7 days of surgery)
研究者
Yang Bin
Principal Investigator
The First Affiliated Hospital of Xiamen University