The effect of beta-caryophyllin on food addiction of wome

Phase 2

Conditions: food addiction.
Overweight and obesity

Registration Number: IRCT20200914048712N1

Lead Sponsor: Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Female

Target Recruitment: 84

Inclusion Criteria

Body mass index between 30 to 99.99 kg/m2
confirmation of food addiction using the relevant questionnaire
being in the age range of 18-50 years

Exclusion Criteria

Reluctance to continue collaborating with the study
Having a weight loss diet in the last two months
Menopause
Continuous use (more than once a week) of vitamin and mineral supplements in the past month
Pregnancy and lactation
Consumption of alcohol, cigarettes (more than 3 cigarettes per day for the past 6 months), tobacco or drugs
Use of weight loss and appetite suppressants
Physical activity started from more than last three weeks
History of neurological diseases or use of psychiatric drugs

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Food addiction. Timepoint: at the baseline and end of study. Method of measurement: Yale Food Addiction Scale (YFAS).

Secondary Outcome Measures

Name	Time	Method
Plasma oxytocin. Timepoint: Before and after the study. Method of measurement: ELISA.;Plasma neuropeptide Y. Timepoint: Before and after the study. Method of measurement: ELISA.;Orexin. Timepoint: Before and after the study. Method of measurement: ELISA.;Mental health. Timepoint: Beginning and end of the study. Method of measurement: Stress-Anxiety-Depression Questionnaire (DASS-21).;Body composition. Timepoint: At the beginning and end of the study. Method of measurement: body composition analyzer.;Appetite. Timepoint: At the beginning and end of the study. Method of measurement: Appetite questionnaire.