Study of Gastro-oesophageal Reflux in Patients Having Had Bariatric Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- post-op gastroœsophageal reflux
研究概览
简要总结
Obesity surgery has become commonplace nowadays. This type of surgery is in full swing and although it is mostly beneficial for the health of the patient (reduction of cardiovascular risks, improvement of self image, reduction of osteo-articular risks, etc...) it is however associated with risks. There are several short and long term complications, excluding the ones related to the anesthesia and the post-op recovery: fistulas, abcesses, infections, dysphagia, risks of endobrachyoesophagus, etc...
The gastroœsophageal reflux remains by far the most common post-op complaint within patients. Patients can experience symptoms as far as 3 years after the surgery. Medical treatment alone can in most cases lighten the symptoms. However, in some cases, this treatment fails and another type of surgery (bypass) must be undertaken, which is psychologically traumatic for the patient.
This retrospective study will analyze a cohort of patients who underwent bariatric surgery (mainly sleeve gastrectomy), in order to identify those at risk of developping gastroœsophageal reflux and how this complication can be avoided in pre-op. The study will also identify cases of invalidating gastroœsophageal reflux that can be solved by obesity surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients who had at least 1 year of postoperative follow-up
排除标准
- •Patients who did not have postoperative gastroœsophageal reflux
- •Patients who stopped their postoperative follow-up
- •Patients with unsufficient data collection
结局指标
主要结局
post-op gastroœsophageal reflux
时间窗: 8 years
gastroœsophageal reflux after the surgical intervention
occurence of other surgical interventions
时间窗: 8 years
occurence of other obesity surgical interventions
existing pre-op gastroœsophageal reflux
时间窗: 8 years
existing gastroœsophageal reflux before the surgical intervention
pre-op BMI
时间窗: 8 years
BMI of the patient before the surgical intervention
medical complications
时间窗: 8 years
occurence of medical complications
number of clips used during the surgery
时间窗: 8 years
number of clips used during the surgery
date of birth
时间窗: 8 years
date of birth of the patient
post-op BMI
时间窗: 8 years
BMI of the patient after the surgical intervention
次要结局
未报告次要终点
研究者
Pierre Wauthy
Head of clinic
Brugmann University Hospital