The Prognostic Capabilities Of A Preoperative Six-Minute Walk Test To Independently Inform Cardiovascular Risk After Major Noncardiac Surgery: Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 试验地点
- 2
- 主要终点
- Measure the additive prognostic value of 6MWT to the RCRI score
研究概览
简要总结
This prospective cohort study aims to determine whether the addition of the 6MWT to the RCRI score improves the risk prediction of postoperative cardiovascular outcomes after noncardiac surgery. In addition, this study will assess whether the patients' reported MET score corresponds to the determined MET score from the 6MWT distance completed.
详细描述
Study investigators propose to undertake a prospective cohort study at the preoperative clinics of the Royal-Victoria and Montreal General Hospitals of McGill University Health Centre. All patients with planned noncardiac surgery under general or regional anesthesia will be considered for inclusion.
Eligible consenting patients will undergo the 6MWT during their preoperative clinical visit, typically occurring within a few weeks before surgery. This test will be performed by a trained health care worker. Patients will walk back and forth along a 20 m corridor, while attempting to cover as much ground as possible in 6 minutes. Patients will be allowed to rest on the chairs while performing the test if necessary. Patients will be encouraged to resume walking as soon as patients feel physically able. The total covered distance in 6 minutes will be measured to the nearest meter.
The RCRI score will be calculated for each study participant.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients fulfilling all the following inclusion criteria will be enrolled:
- •Patients aged ≥ 50 year old and undergoing elective noncardiac surgery, under general anesthesia or regional anesthesia.
- •Patients with planned surgery within 3 months of the preoperative visit.
- •Patients with at least one of the following medical conditions:
- •Hypertension, diabetes mellitus, dyslipidemia, coronary artery disease, chronic kidney disease, transient ischemic attack, stroke, or peripheral vascular disease.
排除标准
- •Patients meeting any of the following criteria will be excluded:
- •Patients with a condition preventing mobilization for 6 minutes.
- •Patients with significant cardiac disease (e.g., low-threshold angina (angina that occurs with minimal exertion), severe aortic stenosis).
- •Patients with severe pulmonary disease restricting mobility.
- •Patients refusing to participate.
- •Patients previously enrolled in the study.
研究组 & 干预措施
Six-minute walk test
All patients will perform six-minute walk test before surgery, in the preoperative clinic
干预措施: Six-minute walk test to perform before surgery (Other)
结局指标
主要结局
Measure the additive prognostic value of 6MWT to the RCRI score
时间窗: At 30 day after surgery
Investigate the additive prognostic value of the 6MWT to the RCRI score for predicting major cardiovascular complications at 30 day after surgery, in patients undergoing noncardiac surgery.
次要结局
- Compare self reported MET score to 6MWT distance(At preoperative clinic visit. Only one measure)
研究者
Amal Bessissow, MD
Principal Investigator
McGill University Health Centre/Research Institute of the McGill University Health Centre