JPRN-UMIN000027010
Recruiting
Phase 2
Allogeneic hematopoietic stem cell transplantation from HLA6/8-4/8 matched related donor for poor prognostic or refractory hematologic malignancy and solid tumor - Ibaraki Children's Hospital phase II study - ICH-HAPLO-16
Ibaraki Children's Hospital0 sites30 target enrollmentApril 17, 2017
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Acute leukemia, malignant lymphoma, and solid tumor
- Sponsor
- Ibaraki Children's Hospital
- Enrollment
- 30
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •(1\)Germ line chromosomal abnormality other than trisomy 21 (2\)Concurrent or prior malignant disease other than the original disease in interest or prior organ transplantation other than hematopoietic cell transplantation (3\)Congenital or acquired immunodeficiency (4\)Uncontrolled fungal, bacterial, or viral infection (including tuberculosis of HIV) (5\)Pregnant, lactating, or highly suspected to be pregnant (6\)Corrected QT interval by Fridericia, more than 0\.45 second (7\)Active hemorrhage in central nervous system, fulfilling grade more than 3 on CTCAE version 4\.0 (8\)Consciousness disturbance, score less than 14 on Glasgow Coma Scale (9\)Obesity, by more than 30% of average weight for age. (10\)Considered to be unsuitable for entry for the study
Outcomes
Primary Outcomes
Not specified
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