Phase1 study of adoptive cell transfer therapy for advanced cancer patients, using stimulated T cells by CH-296.
Phase 1
- Conditions
- unresectable digestive cancer, lung cancer
- Registration Number
- JPRN-UMIN000001835
- Lead Sponsor
- Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 9
Inclusion Criteria
Not provided
Exclusion Criteria
1) Presence of uncontrolled infection 2) Hypersensitivity or autoimmune disease requiring treatments 3) Presence of severe comlications(malignant hypertension, congestive heart failure, severe coronary disease, history of myocardial infarction less than six months prior, pulmonary fibrosis or active interstitial pneumonitis) 4) Inappropriate patients for this study due to severe complications. 5) Active other malignancy, except lesions of "carcinoma in situ" or intramucosal location which are curatively resectable. 6) Medical history of severe hypersensitivity. 7) Severe mental impairment 8) Pregnant or lactating women 9) Inappropriate patients for study judged by the physicians.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adverse events
- Secondary Outcome Measures
Name Time Method response rate