Does Preoperative Administration of Oral Doxycycline Decrease the Colonization Rate of Propionibacterium Acnes in the Dermis of the Shoulder?

Not Applicable

• Conditions: Propionibacterium
• Interventions: Drug: Doxycycline

• Registration Number: NCT02688738
• Lead Sponsor: Rothman Institute Orthopaedics

Brief Summary

The purpose of this study is to evaluate the ability of oral doxycycline to decrease the colonization of Propionibacterium acnes in the dermis of the shoulder.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-03
• Status Verified: 2016-02
• Study First Submitted: 2016-02-11
• Study First Submitted QC: 2016-02-17
• Last Update Submitted: 2016-02-17
• Study First Posted: 2016-02-23
• Last Update Posted: 2016-02-23
• Primary Completion: 2016-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

-All male patients (>18 years of age) undergoing shoulder arthroscopy

Exclusion Criteria

• Female patients
• patients with active acne
• patients who have taken antibiotics in the past month
• doxycycline allergy
• benzoyl peroxide allergy
• clindamycin allergy
• patients with psoriatic/eczematous or other lesions on the shoulder girdle.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Treatment	Doxycycline	Oral doxycycline

Primary Outcome Measures

Name	Time	Method
Quantification of P acnes grown from anaerobic or aerobic culture	within 14 days of surgery