Factors Influencing Occurrence Of Hilar Biliary Stricture In Case of Bile Duct Injury

Completed

• Conditions: Bile Duct Injury
• Interventions: Diagnostic Test: Biliary RMI and CT scan.

• Registration Number: NCT04286763
• Lead Sponsor: University of Oran 1

Brief Summary

The bile duct injury is a complication that occurs mainly after the cholecystectomy. Bile duct stricture is one of complications of this unwitting iatrogenic injury, the outcomes of surgery in this case are worse when the level of the stricture is above the helium.

So what are factors influencing the occurrence of this high level bile duct obstruction ?

Detailed Description

The objective of this study was to answer a simple question, what are the factors influencing the occurrence of high level -called hilar biliary stricture? To answer this question, a retrospective study was carried out on the files of patients operated for biliary stenosis after operative trauma of the bile ducts in our department over a period from January 2010 to May 2018. Only patients operated in biliary stricture (Grade E Strasberg) was included.

A univariate and muntivariate logistic regression analysis was performed to determine the factors influencing the occurrence of hilar stenosis. data entry and analysis was done using SPSS V20.0 software.

Study Timeline

• Study Start: 2010-01-01
• Primary Completion: 2018-05-01
• Study Completion: 2018-09-30
• Status Verified: 2020-02
• Study First Submitted: 2020-02-20
• Study First Submitted QC: 2020-02-24
• Last Update Submitted: 2020-02-24
• Study First Posted: 2020-02-27
• Last Update Posted: 2020-02-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 53

Inclusion Criteria

• all cases with biliary stricture following an operative bile duct injury.

Exclusion Criteria

• cases of biliary stricture following an non operative bile duct injury (Blind or penetrating abdominal trauma , radiological or endoscopic maneuvers).
• cases of biliary stricture following hepatectomy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Low level Stricture	Biliary RMI and CT scan.	Bile duct Stricture (corresponding to E1 and E2 from Strasberg. -According to the classification proposed by Strasberg of operative bile duct injuries).
Hilar stricture	Biliary RMI and CT scan.	Bile duct Stricture (corresponding to E3, E4 and E5 from of Strasberg. -According to the classification proposed by Strasberg of operative bile duct injuries).

Primary Outcome Measures

Name	Time	Method
Factors influencing occurrence of hilar stricture (E3,E4,E5)	from the date of the surgery that caused the biliary injury to the date of transfer to our structure for treatment. in our series, the period varies from 8 weeks to 10 years after the occurrence of operative bile duct injury during initial surgery.	all the variables related to the patient, his disease and the course of the surgical intervention which caused the biliary trauma was recorded.

Trial Locations

Locations (1)

Tidjane Anisse; 🇩🇿 Oran, Algeria