MedPath

Acute and Chronic Responses to Blood Pressure After Exercise

Not Applicable
Completed
Conditions
Arterial Hypertension
Interventions
Other: physical exercises
Registration Number
NCT03160989
Lead Sponsor
Federal University of Uberlandia
Brief Summary

The study will evaluate the variability of blood pressure in postmenopausal and hypertensive women after only one session and after training of ten weeks of combined physical exercises (aerobic and resisted).

Detailed Description

Before starting the training program, all the volunteers will sign the Free and Informed Consent Form (TCLE) and must present a medical certificate releasing the participation. In addition, the volunteers will respond to an anamnesis questionnaire and will undergo an anthropometric evaluation before the experimental sessions. The physical exercise program will be held three times a week for 10 weeks, containing aerobic exercise (exercise treadmill) and resistance exercises (bodybuilding). Initially, a familiarization of the ergometers used will be performed, followed by a session to evaluate the intensity of resistance exercise through a maximal repetition test (1RM), and a session to evaluate aerobic fitness through an incremental treadmill test.

Before starting the training, volunteers will perform a single exercise session, following the same exercise protocol. All the volunteers will be submitted to the evaluation of the blood pressure during 24 hours through the measurement of ambulatory blood pressure (ABPM) in three moments:

* PR: pre-training rest - the volunteers will arrive at the laboratory, will be in rest for 15 minutes and after that they will place the ABPM, without having done any exercise.

* PE: post exercise - upon arriving at the laboratory, the volunteers will be submitted to a single combined exercise session, will have a maximum interval of 20 minutes for the bath and will place the MAP device.

* CR: rest after chronic training - after the end of the 10 weeks of training, the volunteers will be submitted to ABPM, again at rest, with a maximum interval of 72 hours, between the end of the training and the placement of the device.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
14
Inclusion Criteria
  • Women aged between 50 and 70 years;
  • Be in the postmenopausal phase;
  • Be able to practice physical exercise on treadmill and resistance exercises (bodybuilding).
  • Present stage 1 hypertension, according to the guidelines of the Brazilian Society of Hypertension
  • Make use of anti-hypertensive medication, except beta-blockers
  • Participants should be evaluated with a cardiologist beforehand and present a certificate attesting that they are able to perform physical activities.
  • Do not present physical problems or cardiovascular complications that prevent the performance of physical exercises.
Exclusion Criteria
  • Make use of beta-blockers
  • Present history of stroke or acute myocardial infarction;
  • Smoking;
  • Present diagnosis of Diabetes Mellitus.
  • Present renal pathologies
  • Use hormone replacement therapies

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Postmenopausal and hypertensive womenphysical exercisesThe intervention will consist of a single session and after ten weeks of combined physical exercises (aerobic and resisted). All volunteers will participate in the same procedure.
Primary Outcome Measures
NameTimeMethod
Change in ambulatory blood pressure variability in ten weeksAfter ten weeks and before ten weeks of exercise training

The ambulatory blood pressure measurement will be performed for 24 hours. With the information obtained in this measurement, blood pressure variability will be performed.

Secondary Outcome Measures
NameTimeMethod
Comparison resting blood pressureAfter ten weeks and before ten weeks of exercise training

The resting blood pressure is performed after 15 minutes of sitting, measured three times and the mean is calculated for analysis

Anthropometric assessmentsAfter ten weeks and before ten weeks of exercise training

Body composition of the volunteers

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