Effect low dose ketamine in late brain injury from ruptured intracranial aneurysm
- Conditions
- Health Condition 1: I609- Nontraumatic subarachnoid hemorrhage, unspecified
- Registration Number
- CTRI/2023/04/051589
- Lead Sponsor
- ISNACC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1.All aSAH patients 18-70 years of age
2.Admitted to the hospital within 72 hours of ictus
3.Ruptured anterior cerebral circulation aneurysm with subarachnoid hemorrhage on admission cranial computed tomography (CT) scan with modified Fisher grade of 3-4
4.World Federation of Neurological Surgeons (WFNS) grade 1 to 3
5.Informed Consent for participation in the study
1.Refusal of consent
2.Patients with multiple aneurysms
3.Baseline Systolic Blood Pressure (SBP) >200 mm Hg
4.Patients with intraoperative iatrogenic injury or inadvertent clipping of intracranial arteries
5.Any contraindication for the use of ketamine like acute psychosis, previous known ischemic heart diseases.
6.Mean arterial pressure (MAP) increases by more than 20% from baseline (on that day) following infusion
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method